Not a neuroendocrine tumor: A case of hepatocellular carcinoma in ectopic liver tissue in the pancreas

doi:10.14701/ahbps.22-024

Ann Hepatobiliary Pancreat Surg

Published online August 25, 2022; https://doi.org/10.14701/ahbps.22-024

Ana Margarida Correia¹, Cátia Ribeiro¹, Flávio Videira¹, Davide Gigliano², Ana Luísa Cunha², Luís Pedro Afonso², Mariana Peyroteo¹, Rita Canotilho¹, Catarina Baía¹, Fernanda Sousa¹, Joaquim Abreu de Sousa¹

¹Department of Surgical Oncology, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal,
²Department of Anatomical Pathology, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal

Correspondence to: Ana Margarida Correia, MD
Department of Surgical Oncology, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Rua Dr. António Bernardino de Almeida, Porto 4200-072, Portugal
Tel: +351-225-084-000, Fax: +351-225-084-001,
E-mail: i2450@ipoporto.min-saude.pt
ORCID: https://orcid.org/0000-0003-0112-7401

Received May 9, 2022; Revised June 28, 2022; Accepted June 29, 2022.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract: Hepatocellular carcinoma (HCC) accounts for most of the hepatic neoplasms and can also occur in ectopic liver tissue. We present a case of a 55-year-old male complaining of weight loss. The imaging studies reported a 2.9 cm nodule in the pancreatic body, with a neuroendocrine tumor diagnosis by cytology. A corpo-caudal pancreatectomy was performed. Pathology showed a well-differentiated HCC developed in ectopic liver tissue with free margins and no lymph node metastases. HCC presenting in ectopic liver tissue is rare. In this case, the preoperative study did not establish the diagnosis, warranting the need for suspicion of this neoplasm.; Keywords : Hepatocellular carcinoma; Ectopic tissue; Surgical oncology; Differential diagnosis; Pancreatic neoplasms