Table. 3.

Univariate and multivariate analysis for overall survival in matched data (n = 140)

Parameter Univariate Multivariate
HR (95% CI) p-value HR (95% CI) p-value
Age
< 60 yr Ref 0.524
≥ 60 yr 0.83 (0.47–1.45)
Sex
Female Ref 0.900
Male 1.03 (0.61–1.74)
Site
Ampullary Ref < 0.001* 1.56 (0.90–2.70) 0.109
Non-ampullary 2.83 (1.58–5.04)
T stage
T1-T2 Ref 0.001* 1.23 (0.60–2.53) 0.562
T3-T4 2.33 (1.38–3.92)
Nodal stage
N0 Ref < 0.001* 1.62 (0.74–3.55) 0.224
N+ 2.37 (1.43–3.93)
Differentiation
WD/MD Ref 0.207
PD 1.49 (0.80–2.79)
Perineural invasion
Absent Ref 0.086 1.45 (0.82–2.55) 0.197
Present 1.68 (0.92–3.07)
Lymph node ratio
< 0.1 Ref 0.001* 1.03 (0.49–2.17) 0.924
≥ 0.1 2.39 (1.39–4.09)
Recurrence
None Ref < 0.001* 2.91 (1.56–5.42) < 0.001*
Yes 4.64 (2.73–7.87)
Adjuvant CT
Not given Ref 0.087 0.69 (0.40–1.19) 0.188
Given 0.64 (0.38–1.06)

WD, well differentiation; MD, moderately differentiation; PD, poorly differentiation; N0, node-negative; N+, node positive; CT, chemotherapy; HR, hazard ratio; CI, confidence interval.

*Represent p-value significant.

Ann Hepatobiliary Pancreat Surg 2024;28:371-80 https://doi.org/10.14701/ahbps.24-032
© 2024 Ann Hepatobiliary Pancreat Surg