Table. 4.

Table. 4.

Cox-regression analysis to determine factors affecting survival during treatment of oligo-metastatic GBC

Univariate analysis Multivariate analysis


HR (95% CI) p-value HR (95% CI) p-value
Age 1.003 (0.986–1.021) 0.700
Sex
Male Reference
Female 1.112 (0.763–1.621) 0.580
Comorbidity 1.111 (0.757–1.631) 0.590
CA19-9 1.001 (0.998–1.003) 0.533
Preoperative biliary drainage 1.174 (0.695–1.985) 0.547
Incidental GBC
Yes Reference
No 1.45 (1.025–2.049) 0.033 1.865 (1.292–2.693) 0.001
Histologic grade
Well differentiated Reference
Moderately differentiated 2.138 (0.52–8.758) 0.291
Poorly differentiated 2.636 (0.641–10.829) 0.178
Neoadjuvant chemotherapy 1.038 (0.733–1.469) 0.832
Metastasis site
Station 16 Reference
Peritoneum 1.329 (0.914–1.934) 0.137
Liver 1.901 (1.035–3.492) 0.038
Port site 0.623 (0.308–1.263) 0.189
Treatment intent
Radical 0.543 (0.369–0.798) 0.001 0.438 (0.291–0.658) < 0.001
Palliative Reference

HR, hazard ratio; CI, confidence interval; GBC, gallbladder cancer.

Ann Hepatobiliary Pancreat Surg 2023;27:180-8 https://doi.org/10.14701/ahbps.22-111
© 2023 Ann Hepatobiliary Pancreat Surg