Table. 4.

Table. 4.

Multivariable analysis of risk factors for PHLF

Factor Univariate analysis Multivariate analysis


HR (95% CI) p-value HR (95% CI) p-value
Age 0.983 (0.949–1.019) 0.35
BMI 1.059 (0.957–1.171) 0.27
Male sex 8.855 (2.005–39.104) < 0.01
Diabetes 0.960 (0.294–3.133) 0.95
COPD 0.270 (0.068–1.082) 0.06 14.707 (1.750–123.602) 0.01*
Background steatohepatitis 11.701 (4.164–32.875) < 0.01* 11.592 (4.125–32.57) < 0.01*
RLV (Hermes) 1.004 (1.001–1.007) < 0.01*
RLV/Bw 1.397 (1.123–1.737) < 0.01*
RLV/LV(< 28% vs. > 28%) 4.828 (1.836–12.697) < 0.01*
sRLV (Vauthey) (< 27% vs. > 27%) 5.461 (2.032–14.767) < 0.01*
Bilirubin day 1 (< 38 vs. > 38) 10.054 (3.728–27.110) < 0.01* 29.849 (5.112–174.299) < 0.01*
MHV resection 2.263 (0.290–17.640) 0.44

HR, hazard ratio; CI, confidence interval; PHLF, post hepatectomy liver failure; COPD, chronic obstructive pulmonary disease; BMI, body mass index; RLV, remnant liver volume; Bw, body weight; LV, liver volume; sRLV, standardized liver volume; MHV, middle hepatic vein.

*Statistically significant.

Ann Hepatobiliary Pancreat Surg 2022;26:257-62 https://doi.org/10.14701/ahbps.21-159
© 2022 Ann Hepatobiliary Pancreat Surg