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Effect of early and delay starting of enteral feeding in post-pancreaticoduodenectomy patients
Ann Hepatobiliary Pancreat Surg 2019 Feb;23(1):56-60
Published online February 28, 2019;
Copyright © 2019 Korean Association of Hepato-Biliary-Pancreatic Surgery.

Bidhan C. Das, Mozammel Haque, Mohammad Saief Uddin, Md. Nur-E-Elahi, and Zulfiqur Rahman Khan

Department of Hepatobiliary, Pancreatic & Liver Transplant Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Received May 31, 2018; Revised August 5, 2018; Accepted August 18, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Backgrounds/Aims: This study was undertaken to see the effect of early starting of enteral feeding after pancreatoduodenectomy(PD).The results were compared with existing nutritional practice in which enteral feeding started, usually after 7 to 8 postoperative day (PODs) in our institute.
Methods: Thirty patients whome underwent a PD from January 2016 to December 2016 were included in the study. They were divided into two groups, I and II. In group I (n=15), enteral feeding was started from the 2nd POD through the nasojejunal feeding tube along with parenteral partial nutrition support. In group II (n=15), no enteral feeding was given up to seventh and eighth PODs, except the perenteral feeding. Post-operatively, serum albumin levels, total lymphocyte count, total bilirubin levels, serum alkaline phosphate levels were measured for two weeks postoperatively in all the patients for assessing nutritional, immunological and cholestasis status. The mortality, morbidity and lengths of post-operative hospital stay were also recorded.
Results: Postoperatively, the serum albumin level and lymphocyte count decreased from the pre-operative level on the third POD and it gradually increased from the seventh POD onwards in both groups. However, they remained persistently higher in group I than group II. The total bilirubin and alkaline phosphatase decreased to normal levels within the seventh POD in Group I. However, they remained higher than normal levels on POD 14 in Group II. The morbidity and hospital stay was significantly lower in group I than group II.
Conclusions: Early enteral feeding should be considered after PD. This is because it will improve nutritional, immunological status and cholestasis. Therefore,
it reduces morbidity and shortens the hospital stay.
Keywords : Early and delay; Enteral feeding; Pancreatoduodenectomy


February 2019, 23 (1)