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Outcomes of liver resection in patients with colorectal 
liver metastases by laparoscopic or open surgery

Ann Hepatobiliary Pancreat Surg 2018 Aug;22(3):223-30
Published online August 31, 2018
Copyright © 2018 Ann Hepatobiliary Pancreat Surg.

Jae-Ryong Shim1, Seung Duk Lee1, Hyung-Min Park1, Eung-Chang Lee1, Boram Park2, Sung-Sik Han1, Seong Hoon Kim1, Sang Jae Park1

1Center for Liver Cancer, National Cancer Center, 2Biometrics Research Branch and Biostatistics Collaboration Unit, Research Institute, National Cancer Center, Goyang, Korea
Received January 16, 2018; Revised February 13, 2018; Accepted February 16, 2018.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Backgrounds/Aims: Colorectal cancer is found with liver metastases about 20-25% due to characteristics of cancer itself. Approximately 20% of liver metastases are found to be resectable. The objective of this study was to evaluate short-term outcomes of patients who received liver resection with colorectal cancer operation in our center by laparoscopic surgery or open surgery. 
Methods: Short-term outcomes of laparoscopic surgery of liver resection (LSLR) group who underwent liver resection for colorectal liver metastases (CRLM) at a single institute from 2013 to 2016 were compared to those of open surgery of liver resection (OSLR) group. 
Results: A total of 123 patients underwent liver resection for CRLM, including 101 (82.1%) patients in the OSLR group and 22 (17.9%) patients in the LSLR group. There were significant differences in tumor characteristics between the two groups, including synchronous and metachronous (p=0.004), tumor number (p<0.001), and tumor margin (p=0.002). For postoperative outcomes, only the length of hospital stay (LOS) was significantly different between the two groups (8.5 days in LSLR vs. 11 days in OSLR, p<0.001). There was no significant difference in overall rate of postoperative complications between the two groups (9.1% in LSLR vs. 23.8% in OSLR, p=0.158). 
Conclusions: There are no significant differences in postoperative outcomes between LSLR and OSLR except LOS, liver metastasis number, and resection margin. LSLR may be favorable for highly selected patients with CRLM.
Keywords : Colorectal liver metastasis; Laparoscopic surgery; Open surgery; Liver resection


February 2019, 23 (1)