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Clinical usefulness of FDG-PET in patients with hepatocellular carcinoma undergoing surgical resection
Ann Hepatobiliary Pancreat Surg 2017 Nov;21(4):194-8
Published online November 30, 2017
Copyright © 2017 Ann Hepatobiliary Pancreat Surg.

Kyung Jin Cho1, Nam Kyu Choi1, Min Ho Shin1, and A Ri Chong2

1Division of Hepatobiliary Surgery, Department of Surgery and Liver Transplantation, 2Department of Nuclear Medicine, Chosun University Hospital, Gwangju, Korea
Received October 23, 2017; Revised October 24, 2017; Accepted October 27, 2017.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
Backgrounds/Aims: Diagnosis and staging of hepatocellular carcinoma (HCC) is critical because of the variety of treatment methods and prognosis. [18F]fludeoxyglucose-positron emission tomography/computed tomography ([18F]FDG-PET/CT) has been suggested as a diagnostic modality in HCC. The purpose of this study is to evaluate the accuracy of FDG-PET for staging of HCC after surgical resection and histological confirmation. Methods: We retrospectively collected data of 56 patients that underwent FDG-PET before surgical resection for HCC March 2011-May 2017, all of whom were suitable for resection by conventional HCC staging. Results of the maximal standardized uptake value (SUVmax) were compared with histological confirmation. Results: A larger tumor size was related with higher SUVmax (≥4.9). The serum alpha-feto protein was associated with SUVmax. Recurrence rate was higher in patients with higher SUVmax and patients with lower SUVmax had a better survival rate. Conclusions: The SUVmax correlates well with tumor size and factors associated with biological behavior of HCC such as alpha-feto protein, and it could be a beneficial modality in providing prognostic information for HCC. (Ann Hepatobiliary Pancreat Surg 2017;21:194-198)
Keywords : Hepatocellular carcinoma; [18F]fludeoxyglucose positron emission tomography; Standardized uptake value (SUV)

 

November 2017, 21 (4)