Annals of Hepato-Biliary-Pancreatic Surgery

Indexed in /covered by CAS, KoreaScience & DOI/Crossref:eISSN 2508-5859   pISSN 2508-5778

Table. 3.

Table. 3.

Univariate and multivariate analysis of risk factor for disease free survival (DFS)

Characteristics Univariate Multivariate


HR 95% CI p value HR 95% CI p value
Age ≥65 0.936 0.547-1.600 0.891
Male sex 1.481 0.843-2.601 0.205
BMI ≥25 1.535 0.831-2.838 0.223
High ASA class (3) 0.583 0.204-1.666 0.416
Left hepatectomy 1.812 0.954-3.442 0.086
No Caudate lobectomy 1.424 0.552-3.676 0.297
Pre-op biliary drainage 1.380 0.824-2.311 0.240
Pre-op Portal vein embolization 0.690 0.355-1.340 0.299
Pre-op T.bil ≥3 1.444 0.857-2.436 0.186
Pre-op alb <3.5 0.924 0.548-1.557 0.791
Pre-op CA 19-9≥40 1.717 1.002-2.943 0.048 0.616 0.347-1.094 0.098
Tumor size ≥3 cm 1.260 0.738-2.151 0.417
Operation time >390 min 1.143 0.678-1.925 0.690
EBL ≥600 ml 1.380 0.817-2.332 0.235
Lymphovascular invasion 1.206 0.682-2.135 0.566
Perineural invasion 1.961 1.081-3.557 0.030 1.684 1.120-2.530 0.012
Portal vein resection 1.078 0.507-2.295 0.852
Portal vein true invasion 1.117 0.272-4.587 1.000
Positive resection margin 2.123 0.919-4.878 0.081 1.874 1.010-3.447 0.043
T3 versus T2/T1 1.981 0.889-4.414 0.099 1.300 0.853-1.981 0.222
Node metastasis 1.769 0.976-3.203 0.061 2.169 1.540-3.058 0.001
Poorly differentiation 2.165 1.133-4.136 0.021 2.096 1.439-3.054 0.001
No Adjuvant treatment 1.108 0.616-1.992 0.767

HR, hazard ratio; CI, confidence interval; BMI, body mass index; T. Bili, total bilirubin; CA19-9, cancer antigen 19-9; EBL, estimated blood loss

Ann Hepatobiliary Pancreat Surg 2021;25:221-9 https://doi.org/10.14701/ahbps.2021.25.2.221
© 2021 Ann Hepatobiliary Pancreat Surg