Annals of Hepato-Biliary-Pancreatic Surgery

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Table. 1.

Table. 1.

Reported criteria for PHLF diagnosis and to consider LSS

Study PHLF definition Criteria to consider LSS
MARS
Chiu et al. (2006)18 Liver failure within 4 weeks after operation Features of liver failure, including hyperbilirubinemia of total bilirubin greater than 350 mmol/L, or hepatic encephalopathy of grade 2 or above. Patients with PHLF were started considerably earlier, given their rapid course of deterioration. Patients with multiorgan failure in which liver transplantation was not possible were not considered for MARS
Gilg et al. (2018)19 Balzan (50:50) criteria PHLF according to the Balzan (50:50) criteria after major/extended hepatectomy (removal of 4 Couinaud segments)
Rusu et al. (2009)20 NR Rapidly progressive hepatic failure with serum bilirubin level ≥10 mg/dl post-hepatectomy
Saliba et al. (2013)21 Acute hepatic failure after major hepatectomy NR
van de Kerkhove et al. (2003)22 Liver failure following liver resection, with an increasing plasma bilirubin concentration >250 mmol/L PHLF following extensive partial liver resection for liver or biliary malignancies’
PE
Asanuma et al. (2003)23 Postoperative liver failure due to hepatectomy NR
Lee et al. (2017)24 NR Hyperbilirubinemia (>10 mg/dl) with early graft dysfunction
Usami et al. (1989)25 Liver failure after hepatectomy=‘Primary’ liver dysfunction=hepatic encephalopathy, increased serum Bili levels to >10 mg/dl/intrahepatic cholestasis resistant to drug therapy Hepatic encephalopathy, increased serum Bilirubin to >10 mg/dl or intrahepatic cholestasis resistant to drug therapy
Yonekawa et al. (2005)26 Acute severe liver dysfunction, with a total serum bilirubin level >5mg/dl and an ensuing grade 2 or higher coma that developed within 1 month after surgery NR

NR, not reported

Ann Hepatobiliary Pancreat Surg 2021;25:171-8 https://doi.org/10.14701/ahbps.2021.25.2.171
© 2021 Ann Hepatobiliary Pancreat Surg